Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation

Human pluripotent stem cells (hPSCs) are a powerful tool for modelling human development. In recent years, hPSCs have become central in cell-based therapies for neurodegenerative diseases given their potential to replace affected neurons. However, directing hPSCs into specific neuronal types is comp...

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Publicado en:Mol Neurobiol
Main Authors: Comella-Bolla, Andrea, Orlandi, Javier G., Miguez, Andrés, Straccia, Marco, García-Bravo, María, Bombau, Georgina, Galofré, Mireia, Sanders, Phil, Carrere, Jordi, Segovia, José Carlos, Blasi, Joan, Allen, Nicholas D., Alberch, Jordi, Soriano, Jordi, Canals, Josep M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253531/
https://ncbi.nlm.nih.gov/pubmed/32356172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-01907-4
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