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Late Protective Effect of Netrin-1 in the Murine Acetaminophen Hepatotoxicity Model

Acetaminophen (APAP) overdose-induced acute liver failure is an important clinical problem in the United States and the current antidote N-acetylcysteine, has a short early therapeutic window. Since most patients present late to the clinic, there is need for novel late-acting therapeutic options. Th...

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Publicat a:Toxicol Sci
Autors principals: Duan, Luqi, Woolbright, Benjamin L, Jaeschke, Hartmut, Ramachandran, Anup
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253199/
https://ncbi.nlm.nih.gov/pubmed/32207522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa041
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