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Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis

Galectin-3 (formerly known as Mac-2), encoded by the LGALS3 gene, is proposed to regulate macrophage adhesion, chemotaxis, and apoptosis. We investigated the role of galectin-3 in determining the inflammatory profile of macrophages and composition of atherosclerotic plaques. APPROACH AND RESULTS: We...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Di Gregoli, Karina, Somerville, Michelle, Bianco, Rosaria, Thomas, Anita C., Frankow, Aleksandra, Newby, Andrew C., George, Sarah J., Jackson, Christopher L., Johnson, Jason L.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253188/
https://ncbi.nlm.nih.gov/pubmed/32295421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314252
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