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Differential effects of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 on atherosclerosis and monocyte/macrophage invasion

AIMS: MMPs contribute to atherosclerotic plaque progression and instability, but the relative potency of their endogenous tissue inhibitors of metalloproteinases (TIMPs) as protective factors has not been defined. We therefore investigated the impact of TIMP-1 and TIMP-2 knockout on atherosclerotic...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Di Gregoli, Karina, George, Sarah J., Jackson, Christopher L., Newby, Andrew C., Johnson, Jason L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724937/
https://ncbi.nlm.nih.gov/pubmed/26645981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv268
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