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Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion

Gliomas are primary brain tumors characterized by their invasiveness and heterogeneity. Specific histological patterns such as pseudopalisades, microvascular proliferation, mesenchymal transformation and necrosis characterize the histological heterogeneity of high-grade gliomas. Our laboratory has d...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Comba, Andrea, Dunn, Patrick J, Kish, Phillip E, Kadiyala, Padma, Kahana, Alon, Castro, Maria G, Lowenstein, Pedro R
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253033/
https://ncbi.nlm.nih.gov/pubmed/32338655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/60939
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