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Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion

Gliomas are primary brain tumors characterized by their invasiveness and heterogeneity. Specific histological patterns such as pseudopalisades, microvascular proliferation, mesenchymal transformation and necrosis characterize the histological heterogeneity of high-grade gliomas. Our laboratory has d...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Comba, Andrea, Dunn, Patrick J, Kish, Phillip E, Kadiyala, Padma, Kahana, Alon, Castro, Maria G, Lowenstein, Pedro R
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253033/
https://ncbi.nlm.nih.gov/pubmed/32338655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/60939
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