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In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immunotherapy in patients with metastatic cutaneous melanoma

BACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved the outcome in metastatic cutaneous melanoma (CM). However, therapy response is limited to subgroups of patients and clinically useful predictive biomarkers are lacking. METHODS: To discover treatment-related systemic change...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Babačić, Haris, Lehtiö, Janne, Pico de Coaña, Yago, Pernemalm, Maria, Eriksson, Hanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253007/
https://ncbi.nlm.nih.gov/pubmed/32457125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000204
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