Robust CD8(+) T-cell proliferation and diversification after mogamulizumab in patients with adult T-cell leukemia-lymphoma

Skin-related adverse events (AEs) occur frequently in adult T-cell leukemia-lymphoma (ATL) patients treated with mogamulizumab, a humanized anti-CCR4 monoclonal antibody. This study was undertaken to elucidate the mechanisms of mogamulizumab-induced skin-related AEs. We analyzed the T-cell receptor...

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Detalles Bibliográficos
Publicado en:Blood Adv
Autores principales: Saito, Masato, Ishii, Toshihiko, Urakawa, Itaru, Matsumoto, Asuka, Masaki, Ayako, Ito, Asahi, Kusumoto, Shigeru, Suzuki, Susumu, Takahashi, Takeshi, Morita, Akimichi, Inagaki, Hiroshi, Iida, Shinsuke, Ishida, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2020
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252545/
https://ncbi.nlm.nih.gov/pubmed/32433748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001641
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