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TRUST4RD: tool for reducing uncertainties in the evidence generation for specialised treatments for rare diseases

BACKGROUND: Many treatments developed for rare diseases will have an Orphan Medicinal Product (OMP) designation, indicating that they are likely to deliver benefit in an area of high unmet need. Their approval may be based on a small or uncontrolled trial, as randomised controlled trials (RCTs) of s...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Annemans, Lieven, Makady, Amr
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251888/
https://ncbi.nlm.nih.gov/pubmed/32456653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-01370-3
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