Managing clustering effects and learning effects in the design and analysis of multicentre randomised trials: a survey to establish current practice

BACKGROUND: Patient outcomes can depend on the treating centre, or health professional, delivering the intervention. A health professional’s skill in delivery improves with experience, meaning that outcomes may be associated with learning. Considering differences in intervention delivery at trial de...

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Опубликовано в: :Trials
Главные авторы: Conroy, Elizabeth J., Blazeby, Jane M., Burnside, Girvan, Cook, Jonathan A., Gamble, Carrol
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Methodology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251810/
https://ncbi.nlm.nih.gov/pubmed/32460815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04318-x
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