Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial

IMPORTANCE: Deprescribing of antihypertensive medications is recommended for some older patients with polypharmacy and multimorbidity when the benefits of continued treatment may not outweigh the harms. OBJECTIVE: This study aimed to establish whether antihypertensive medication reduction is possibl...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Sheppard, James P., Burt, Jenni, Lown, Mark, Temple, Eleanor, Lowe, Rebecca, Fraser, Rosalyn, Allen, Julie, Ford, Gary A, Heneghan, Carl, Hobbs, F. D. Richard, Jowett, Sue, Kodabuckus, Shahela, Little, Paul, Mant, Jonathan, Mollison, Jill, Payne, Rupert A., Williams, Marney, Yu, Ly-Mee, McManus, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251449/
https://ncbi.nlm.nih.gov/pubmed/32453368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.4871
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