OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial

INTRODUCTION: Recent evidence suggests that larger blood pressure reductions and multiple antihypertensive drugs may be harmful in older people, particularly frail individuals with polypharmacy and multimorbidity. However, there is a lack of evidence to support deprescribing of antihypertensives, wh...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Sheppard, James P, Burt, Jenni, Lown, Mark, Temple, Eleanor, Benson, John, Ford, Gary A, Heneghan, Carl, Hobbs, F D Richard, Jowett, Sue, Little, Paul, Mant, Jonathan, Mollison, Jill, Nickless, Alecia, Ogburn, Emma, Payne, Rupert, Williams, Marney, Yu, Ly-Mee, McManus, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
General practice / Family practice
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173263/
https://ncbi.nlm.nih.gov/pubmed/30287610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-022930
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