CSN6–TRIM21 axis instigates cancer stemness during tumorigenesis

BACKGROUND: Cancer stem cells (CSCs) are responsible for tumour initiation, metastasis and recurrence. However, the mechanism of CSC formation, maintenance and expansion in colorectal cancer (CRC) remains poorly characterised. METHODS: The role of COP9 signalosome subunit 6 (CSN6) in regulating canc...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Qin, Baifu, Zou, Shaomin, Li, Kai, Wang, Huashe, Wei, Wenxia, Zhang, Boyu, Xiao, Lishi, Choi, Hyun Ho, Tang, Qin, Huang, Dandan, Liu, Qingxin, Pan, Qihao, Meng, Manqi, Fang, Lekun, Lee, Mong-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250844/
https://ncbi.nlm.nih.gov/pubmed/32225170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0779-9
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