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Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells

Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are typically acquired during tetraploidization are responsible for driving tumorigenesis. However, tetraploid cel...

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Veröffentlicht in:eLife
Hauptverfasser: Baudoin, Nicolaas C, Nicholson, Joshua M, Soto, Kimberly, Martin, Olga, Chen, Jing, Cimini, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250578/
https://ncbi.nlm.nih.gov/pubmed/32347795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54565
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