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Use of Hydroxylamines, Hydroxamic Acids, Oximes and Amines as Nucleophiles in the Zbiral Oxidative Deamination of N-Acetyl Neuraminic Acid. Isolation and Characterization of Novel Mono- and Disubstitution Products

The oxidative deamination of N-nitroso N-acetylneuraminic acid (NeuAc) derivatives is a useful reaction for the formation of 5-desamino-5-hydroxy NeuAc derivatives and their stereoisomers. We demonstrated previously that replacement of the classical nucleophile in these reactions, acetic acid, by ph...

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Publicado en:Carbohydr Res
Main Authors: Hawsawi, Mohammed, Pirrone, Michael G., Wickramasinghe, Anura, Crich, David
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250565/
https://ncbi.nlm.nih.gov/pubmed/32171977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2020.107921
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