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Genetic Variants in the Activation of the Brown-Like Adipocyte Pathway and the Risk for Severe Obesity

BACKGROUND: Regular physical activity has an important role in energy expenditure and combats the development of obesity. During exercise, PPARGC1A is overexpressed, stimulating an increase of the expression of FNDC5. This protein is cleaved to release the hormone irisin, which activates a browning...

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Detalhes bibliográficos
Publicado no:Obes Facts
Main Authors: da Fonseca, Ana Carolina Proença, da Fonseca, Guilherme Proença, Marchesini, Bruna, Voigt, Danielle Dutra, Campos Junior, Mario, Zembrzuski, Verônica Marques, Carneiro, João Regis Ivar, Nogueira Neto, José Firmino, Cabello, Pedro Hernan, Cabello, Giselda Maria Kalil
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250364/
https://ncbi.nlm.nih.gov/pubmed/32325455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000505666
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