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Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy

High-throughput drug screening of patient-derived organoids offers an attractive platform to determine cancer treatment efficacy. Here, selective plane illumination microscopy (SPIM) was used to determine treatment response in organoids with endogenous fluorescence from the metabolic coenzymes NAD(P...

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Publicat a:Biomed Opt Express
Autors principals: Favreau, Peter F., He, Jiaye, Gil, Daniel A., Deming, Dustin A., Huisken, Jan, Skala, Melissa C.
Format: Artigo
Idioma:Inglês
Publicat: Optical Society of America 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249841/
https://ncbi.nlm.nih.gov/pubmed/32499946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.389164
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