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Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy

High-throughput drug screening of patient-derived organoids offers an attractive platform to determine cancer treatment efficacy. Here, selective plane illumination microscopy (SPIM) was used to determine treatment response in organoids with endogenous fluorescence from the metabolic coenzymes NAD(P...

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Detalhes bibliográficos
Publicado no:Biomed Opt Express
Main Authors: Favreau, Peter F., He, Jiaye, Gil, Daniel A., Deming, Dustin A., Huisken, Jan, Skala, Melissa C.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249841/
https://ncbi.nlm.nih.gov/pubmed/32499946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.389164
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