Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease

BACKGROUND: Tubulointerstitial fibrosis represents the key underlying pathology of Chronic Kidney Disease (CKD), yet treatment options remain limited. In this study, we investigated the role of connexin43 (Cx43) hemichannel-mediated adenosine triphosphate (ATP) release in purinergic-mediated disasse...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Price, Gareth W., Chadjichristos, Christos E., Kavvadas, Panagiotis, Tang, Sydney C. W., Yiu, Wai Han, Green, Colin R., Potter, Joe A., Siamantouras, Eleftherios, Squires, Paul E., Hills, Claire E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249671/
https://ncbi.nlm.nih.gov/pubmed/32450899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00558-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi