Mass spectrometry-based stable-isotope tracing uncovers metabolic alterations in pyruvate kinase-deficient Aedes aegypti mosquitoes

A recent in vitro characterization of a recombinant pyruvate kinase (PK) from Aedes aegypti mosquitoes demonstrated that the enzyme is uniquely regulated by multiple allosteric effectors. Here, we further explored PK gene and protein expression, and enzymatic activity in key metabolic tissues of mos...

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Xehetasun bibliografikoak
Argitaratua izan da:Insect Biochem Mol Biol
Egile Nagusiak: Petchampai, Natthida, Isoe, Jun, Horvath, Thomas D., Dagan, Shai, Tan, Lin, Lorenzi, Philip L., Hawke, David H., Scaraffia, Patricia Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249512/
https://ncbi.nlm.nih.gov/pubmed/32276114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2020.103366
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