Ubiquitin ligase CHAF1B induces cisplatin resistance in lung adenocarcinoma by promoting NCOR2 degradation

BACKGROUND: Lung cancer is the most common malignant tumor in the world. The Whole-proteome microarray showed that ubiquitin ligase chromatin assembly factor 1 subunit B (CHAF1B) expression in A549/DDP cells is higher than in A549 cells. Our study explored the molecular mechanism of CHAF1B affecting...

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Publicado en:Cancer Cell Int
Autores principales: Gong, Lian, Hu, Yi, He, Dong, Zhu, Yuxing, Xiang, Liang, Xiao, Mengqing, Bao, Ying, Liu, Xiaoming, Zeng, Qinghai, Liu, Jianye, Zhou, Ming, Zhou, Yanhong, Cheng, Yaxin, Zhang, Yeyu, Deng, Liping, Zhu, Rongrong, Lan, Hua, Cao, Ke
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249347/
https://ncbi.nlm.nih.gov/pubmed/32508530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01263-2
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