WDHD1 Leads to Cisplatin Resistance by Promoting MAPRE2 Ubiquitination in Lung Adenocarcinoma

Ubiquitin ligases have been shown to regulate drug sensitivity. This study aimed to explore the role of the ubiquitin ligase WD repeat and HMG-box DNA binding protein 1 (WDHD1) in regulating cisplatin sensitivity in lung adenocarcinoma (LUAD). A quantitative analysis of the global proteome identifie...

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Gepubliceerd in:Front Oncol
Hoofdauteurs: Gong, Lian, Xiao, Mengqing, He, Dong, Hu, Yi, Zhu, Yuxing, Xiang, Liang, Bao, Ying, Liu, Xiaoming, Zeng, Qinghai, Liu, Jianye, Zhou, Ming, Zhou, Yanhong, Cheng, Yaxin, Zhang, Yeyu, Deng, Liping, Zhu, Rongrong, Lan, Hua, Cao, Ke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Oncology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212426/
https://ncbi.nlm.nih.gov/pubmed/32426268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00461
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