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Facile Synthesis of NH-Free 5-(Hetero)Aryl-Pyrrole-2-Carboxylates by Catalytic C–H Borylation and Suzuki Coupling

A convenient two-step preparation of NH-free 5-aryl-pyrrole-2-carboxylates is described. The synthetic route consists of catalytic borylation of commercially available pyrrole-2-carboxylate ester followed by Suzuki coupling without going through pyrrole N–H protection and deprotection steps. The res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Kanwal, Saba, Ann, Noor-ul-, Fatima, Saman, Emwas, Abdul-Hamid, Alazmi, Meshari, Gao, Xin, Ibrar, Maha, Zaib Saleem, Rahman Shah, Chotana, Ghayoor Abbas
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248765/
https://ncbi.nlm.nih.gov/pubmed/32365945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25092106
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