Effect of VX-765 on the transcriptome profile of mice spinal cords with acute injury

Previous studies have shown that caspase-1 plays an important role in the acute inflammatory response of spinal cord injury (SCI). VX-765, a novel and irreversible caspase-1 inhibitor, has been reported to effectively intervene in inflammation. However, the effect of VX-765 on genome-wide transcript...

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Udgivet i:Mol Med Rep
Main Authors: Chen, Jing, Chen, Yu-Qing, Wang, Sai-Nan, Duan, Fei-Xiang, Shi, Yu-Jiao, Ding, Shu-Qin, Hu, Jian-Guo, Lü, He-Zuo
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248530/
https://ncbi.nlm.nih.gov/pubmed/32377730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11129
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