VX-765 reduces neuroinflammation after spinal cord injury in mice

Inflammation is a major cause of neuronal injury after spinal cord injury. We hypothesized that inhibiting caspase-1 activation may reduce neuroinflammation after spinal cord injury, thus producing a protective effect in the injured spinal cord. A mouse model of T9 contusive spinal cord injury was e...

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Bibliographische Detailangaben
Veröffentlicht in:Neural Regen Res
Hauptverfasser: Chen, Jing, Chen, Yu-Qing, Shi, Yu-Jiao, Ding, Shu-Qin, Shen, Lin, Wang, Rui, Wang, Qi-Yi, Zha, Cheng, Ding, Hai, Hu, Jian-Guo, Lü, He-Zuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer - Medknow 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328782/
https://ncbi.nlm.nih.gov/pubmed/33510091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.306096
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