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Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

The present study evaluated the effect of combining inhibitors (17-AAG) of heat shock protein 90 (HSP90) and autophagy (3-MA) on apoptosis using an incomplete thermal ablation animal model. A total of 28 orthotopic mice with hepatocellular carcinoma were randomly divided into 4 groups to receive dif...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Chen, Fen, Xie, Haiyang, Bao, Haiwei, Violetta, Laurencia, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248472/
https://ncbi.nlm.nih.gov/pubmed/32319654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11080
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