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Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition
The chaperone HSP70 promotes the survival of cells exposed to many different types of stresses, and is also potently anti-apoptotic. The major stress-induced form of this protein, HSP70–1, is overexpressed in a number of human cancers, yet is negligibly expressed in normal cells. Silencing of the ge...
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| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928135/ https://ncbi.nlm.nih.gov/pubmed/24100579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.26720 |
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