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Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence
Hypoxia/reoxygenation (H/R) may play an important role via senescence in the mechanism of osteoarthritis (OA) development. The synovial membrane is highly sensitive to H/R due to its oxygen consumption feature. Excessive mechanical loads and oxidative stress caused by H/R induce a senescence-associa...
Shranjeno v:
| izdano v: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
D.A. Spandidos
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7248463/ https://ncbi.nlm.nih.gov/pubmed/32377698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11102 |
| Oznake: |
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