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Growth/Differentiation Factor-15 (GDF-15): From Biomarker to Novel Targetable Immune Checkpoint

Growth/differentiation factor-15 (GDF-15), also named macrophage inhibitory cytokine-1, is a divergent member of the transforming growth factor β superfamily. While physiological expression is barely detectable in most somatic tissues in humans, GDF-15 is abundant in placenta. Elsewhere, GDF-15 is o...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wischhusen, Jörg, Melero, Ignacio, Fridman, Wolf Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248355/
https://ncbi.nlm.nih.gov/pubmed/32508832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00951
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