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Role of GDF15 (Growth and Differentiation factor 15) In Pulmonary Oxygen Toxicity

GDF15 (Growth and differentiation factor 15) is a secreted cytokine, a direct target of p53 and plays a role in cell proliferation and apoptosis. It is induced by oxidative stress and has anti-apoptotic effects. The role of GDF15 in hyperoxic lung injury is unknown. We tested the hypothesis that GDF...

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Publicado en:Toxicol In Vitro
Main Authors: Tiwari, Kirti Kumar, Moorthy, Bhagavatula, Lingappan, Krithika
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553106/
https://ncbi.nlm.nih.gov/pubmed/26004619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2015.05.008
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