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Role of GDF15 (Growth and Differentiation factor 15) In Pulmonary Oxygen Toxicity
GDF15 (Growth and differentiation factor 15) is a secreted cytokine, a direct target of p53 and plays a role in cell proliferation and apoptosis. It is induced by oxidative stress and has anti-apoptotic effects. The role of GDF15 in hyperoxic lung injury is unknown. We tested the hypothesis that GDF...
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Publicado no: | Toxicol In Vitro |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4553106/ https://ncbi.nlm.nih.gov/pubmed/26004619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2015.05.008 |
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