RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of incident disease, as a screening test for subclinic...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Penn-Nicholson, Adam, Mbandi, Stanley Kimbung, Thompson, Ethan, Mendelsohn, Simon C., Suliman, Sara, Chegou, Novel N., Malherbe, Stephanus T., Darboe, Fatoumatta, Erasmus, Mzwandile, Hanekom, Willem A., Bilek, Nicole, Fisher, Michelle, Kaufmann, Stefan H. E., Winter, Jill, Murphy, Melissa, Wood, Robin, Morrow, Carl, Van Rhijn, Ildiko, Moody, Branch, Murray, Megan, Andrade, Bruno B., Sterling, Timothy R., Sutherland, Jayne, Naidoo, Kogieleum, Padayatchi, Nesri, Walzl, Gerhard, Hatherill, Mark, Zak, Daniel, Scriba, Thomas J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248089/
https://ncbi.nlm.nih.gov/pubmed/32451443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65043-8
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