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VAGINAL SUPPOSITORIES CONTAINING SHetA2 TO TREAT CERVICAL DYSPLASIA: PHARMACOKINETICS OF DAILY DOSES AND PRELIMINARY SAFETY PROFILE
SHetA2 is a new drug with potential to treat cervical dysplasia, but only 0.02% of the dose is absorbed into the cervix after oral administration. In contrast, 23.9% of the dose is absorbed into the cervix after vaginal administration. This study determines the pharmacokinetic (PK) and pharmacodynam...
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| Izdano u: | J Pharm Sci |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247943/ https://ncbi.nlm.nih.gov/pubmed/32113976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.02.016 |
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