Low-Molecular-Weight Heparin Reduces Ventilation-Induced Lung Injury through Hypoxia Inducible Factor-1α in a Murine Endotoxemia Model

Patients with sepsis frequently require mechanical ventilation (MV) to survive. However, MV has been shown to induce the production of proinflammatory cytokines, causing ventilator-induced lung injury (VILI). It has been demonstrated that hypoxia-inducible factor (HIF)-1α plays a crucial role in ind...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Li, Li-Fu, Liu, Yung-Yang, Lin, Shih-Wei, Chang, Chih-Hao, Chen, Ning-Hung, Hung, Chen-Yiu, Lee, Chung-Shu
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247708/
https://ncbi.nlm.nih.gov/pubmed/32353952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093097
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