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The Cannabinoid Receptor CB1 Stabilizes Sperm Chromatin Condensation Status During Epididymal Transit by Promoting Disulphide Bond Formation

The cannabinoid receptor CB1 regulates differentiation of spermatids. We recently characterized spermatozoa from caput epididymis of CB1-knock-out mice and identified a considerable number of sperm cells with chromatin abnormality such as elevated histone content and poorly condensed chromatin. In t...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Chioccarelli, Teresa, Manfrevola, Francesco, Porreca, Veronica, Fasano, Silvia, Altucci, Lucia, Pierantoni, Riccardo, Cobellis, Gilda
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247701/
https://ncbi.nlm.nih.gov/pubmed/32354121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093117
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