The Cannabinoid Receptor CB1 Stabilizes Sperm Chromatin Condensation Status During Epididymal Transit by Promoting Disulphide Bond Formation

The cannabinoid receptor CB1 regulates differentiation of spermatids. We recently characterized spermatozoa from caput epididymis of CB1-knock-out mice and identified a considerable number of sperm cells with chromatin abnormality such as elevated histone content and poorly condensed chromatin. In t...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Chioccarelli, Teresa, Manfrevola, Francesco, Porreca, Veronica, Fasano, Silvia, Altucci, Lucia, Pierantoni, Riccardo, Cobellis, Gilda
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247701/
https://ncbi.nlm.nih.gov/pubmed/32354121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093117
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