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Proteomic Analysis of Myocardia Containing the Obscurin R4344Q Mutation Linked to Hypertrophic Cardiomyopathy

Obscurin is a giant cytoskeletal protein with structural and regulatory roles encoded by the OBSCN gene. Recently, mutations in OBSCN were associated with the development of different forms of cardiomyopathies, including hypertrophic cardiomyopathy (HCM). We previously reported that homozygous mice...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Hu, Li-Yen R., Kontrogianni-Konstantopoulos, Aikaterini
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247546/
https://ncbi.nlm.nih.gov/pubmed/32528308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00478
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