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Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction

Several recent studies have shown that chromatin, the DNA-protein complex that packages genomic DNA, has an important function in learning and memory. Dynamic chromatin modification via histone deacetylase (HDAC) inhibitors and histone acetyltransferases (HATs) may enhance hippocampal synaptic plast...

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Bibliographic Details
Published in:Behav Neurosci
Main Authors: Lattal, K. Matthew, Barrett, Ruth, Wood, Marcelo A.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247429/
https://ncbi.nlm.nih.gov/pubmed/17907845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/0735-7044.121.5.1125
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