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The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective
Metformin therapy lowers blood glucose in type 2 diabetes by targeting various pathways including hepatic gluconeogenesis. Despite widespread clinical use of metformin the molecular mechanisms by which it inhibits gluconeogenesis either acutely through allosteric and covalent mechanisms or chronical...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247334/ https://ncbi.nlm.nih.gov/pubmed/32375255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093240 |
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