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The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective
Metformin therapy lowers blood glucose in type 2 diabetes by targeting various pathways including hepatic gluconeogenesis. Despite widespread clinical use of metformin the molecular mechanisms by which it inhibits gluconeogenesis either acutely through allosteric and covalent mechanisms or chronical...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247334/ https://ncbi.nlm.nih.gov/pubmed/32375255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093240 |
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