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The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation

S-Acylation of the SNARE protein SNAP25 (synaptosome-associated protein of 25 kDa) is mediated by a subset of Golgi zinc finger DHHC-type palmitoyltransferase (zDHHC) enzymes, particularly zDHHC17. The ankyrin repeat domain of zDHHC17 interacts with a short linear motif known as the zDHHC ankyrin re...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Salaun, Christine, Greaves, Jennifer, Tomkinson, Nicholas C. O., Chamberlain, Luke H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247313/
https://ncbi.nlm.nih.gov/pubmed/32317281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012726
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