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The Hydrophobic Cysteine-rich Domain of SNAP25 Couples with Downstream Residues to Mediate Membrane Interactions and Recognition by DHHC Palmitoyl Transferases

SNAP25 is synthesized as a soluble protein but must associate with the plasma membrane to function in exocytosis; however, this membrane-targeting pathway is poorly defined. SNAP25 contains a palmitoylated cysteine-rich domain with four cysteines, and we show that coexpression of specific DHHC palmi...

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Main Authors: Greaves, Jennifer, Prescott, Gerald R., Fukata, Yuko, Fukata, Masaki, Salaun, Christine, Chamberlain, Luke H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655257/
https://ncbi.nlm.nih.gov/pubmed/19158383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0944
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