The regulatory G protein signaling complex, Gβ5–R7, promotes glucose- and extracellular signal–stimulated insulin secretion

G protein–coupled receptors (GPCRs) are important modulators of glucose-stimulated insulin secretion, essential for maintaining energy homeostasis. Here we investigated the role of Gβ5–R7, a protein complex consisting of the atypical G protein β subunit Gβ5 and a regulator of G protein signaling of...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Qiang, Henry, Taylor A. N., Pronin, Alexey N., Jang, Geeng-Fu, Lubaczeuski, Camila, Crabb, John W., Bernal-Mizrachi, Ernesto, Slepak, Vladlen Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247291/
https://ncbi.nlm.nih.gov/pubmed/32229584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011534
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