ロード中...
Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor
Pilocarpine is a prototypical drug used to treat glaucoma and dry mouth and is classified as either a full or partial muscarinic agonist. Here, we report several unexpected results pertaining to its interaction with muscarinic M3 receptor (M3R). We found that pilocarpine was 1000 times less potent i...
保存先:
| 出版年: | Mol Pharmacol |
|---|---|
| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635516/ https://ncbi.nlm.nih.gov/pubmed/28893976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109678 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|