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A Novel Zinc Chelator, 1H10, Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating Zinc Toxicity and AMPK Activation

Previous studies in our lab revealed that chemical zinc chelation or zinc transporter 3 (ZnT3) gene deletion suppresses the clinical features and neuropathological changes associated with experimental autoimmune encephalomyelitis (EAE). In addition, although protective functions are well documented...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Choi, Bo Young, Jeong, Jeong Hyun, Eom, Jae-Won, Koh, Jae-Young, Kim, Yang-Hee, Suh, Sang Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247014/
https://ncbi.nlm.nih.gov/pubmed/32397660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093375
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