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Comparative Cerebroprotective Potential of d- and l-Carnosine Following Ischemic Stroke in Mice

l-carnosine is an attractive therapeutic agent for acute ischemic stroke based on its robust preclinical cerebroprotective properties and wide therapeutic time window. However, large doses are needed for efficacy because carnosine is rapidly degraded in serum by carnosinases. The need for large dose...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jain, Saurabh, Kim, Eun-Sun, Kim, Donghyun, Burrows, David, De Felice, Milena, Kim, Minyeong, Baek, Seung-Hoon, Ali, Ali, Redgrave, Jessica, Doeppner, Thorsten R., Gardner, Iain, Bae, Ok-Nam, Majid, Arshad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246848/
https://ncbi.nlm.nih.gov/pubmed/32357505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093053
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