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Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage

BACKGROUND AND PURPOSE: Despite the rapidly increasing global burden of ischemic stroke, no therapeutic options for neuroprotection against stroke currently exist. Recent studies have shown that autophagy plays a key role in ischemic neuronal death and treatments that target autophagy may represent...

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Detalhes bibliográficos
Main Authors: Baek, Seung-Hoon, Noh, Ah Reum, Kim, Kyeong-A, Akram, Muhammad, Shin, Young-Jun, Kim, Eun-Sun, Yu, Seong Woon, Majid, Arshad, Bae, Ok-Nam
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211270/
https://ncbi.nlm.nih.gov/pubmed/24938837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.005183
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