Identification of Lenalidomide Sensitivity and Resistance Mechanisms in Non-Del(5q) Myelodysplastic Syndromes

Whereas lenalidomide is an effective therapy for del(5q) MDS patients, a minority of non-del(5q) MDS patients achieve hematologic improvement with lenalidomide. We used computational biology modeling and digital drug simulation to examine genomic data from 56 non-del(5q) MDS patients treated with le...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Drusbosky, Leylah M., Cogle, Christopher R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246771/
https://ncbi.nlm.nih.gov/pubmed/32397113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093323
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