Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects

We have designed and synthesized two novel cobalt coordination compounds using bumetanide (bum) and indomethacin (ind) therapeutic agents. The anti-inflammatory effects of cobalt metal complexes with ind and bum were assayed in lipopolysaccharide stimulated RAW 264.7 macrophages by inhibition of nit...

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Publicado no:Int J Mol Sci
Main Authors: Navas, Arturo, Jannus, Fatin, Fernández, Belén, Cepeda, Javier, Medina O’Donnell, Marta, Díaz-Ruiz, Luis, Sánchez-González, Cristina, Llopis, Juan, Seco, José M., Rufino-Palomares, E., Lupiáñez, José Antonio, Gómez-Ruiz, Santiago, Quiles, José Luis, Battino, Maurizio, Choquesillo-Lazarte, Duane, Ruiz-Muelle, Ana Belén, Fernández, Ignacio, Reyes-Zurita, Fernando, Rodríguez-Diéguez, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246571/
https://ncbi.nlm.nih.gov/pubmed/32365648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093146
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