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HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment

HIV-1 infection is frequently associated with low bone density, which can progress to osteoporosis leading to a high risk of fractures. Only a few mechanisms have been proposed to explain the enhanced osteolysis in the context of HIV-1 infection. As macrophages are involved in bone homeostasis and a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Mascarau, Rémi, Bertrand, Florent, Labrousse, Arnaud, Gennero, Isabelle, Poincloux, Renaud, Maridonneau-Parini, Isabelle, Raynaud-Messina, Brigitte, Vérollet, Christel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246503/
https://ncbi.nlm.nih.gov/pubmed/32365752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093154
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