Anomalous AMPK-regulated angiotensin AT(1)R expression and SIRT1-mediated mitochondrial biogenesis at RVLM in hypertension programming of offspring to maternal high fructose exposure

BACKGROUND: Tissue oxidative stress, sympathetic activation and nutrient sensing signals are closely related to adult hypertension of fetal origin, although their interactions in hypertension programming remain unclear. Based on a maternal high-fructose diet (HFD) model of programmed hypertension, w...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Chao, Yung-Mei, Wu, Kay L. H., Tsai, Pei-Chia, Tain, You-Lin, Leu, Steve, Lee, Wei-Chia, Chan, Julie Y. H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245869/
https://ncbi.nlm.nih.gov/pubmed/32446297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00660-z
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