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Prenatal Metformin Therapy Attenuates Hypertension of Developmental Origin in Male Adult Offspring Exposed to Maternal High-Fructose and Post-Weaning High-Fat Diets

Widespread consumption of a Western diet, comprised of highly refined carbohydrates and fat, may play a role in the epidemic of hypertension. Hypertension can take origin from early life. Metformin is the preferred treatment for type 2 diabetes. We examined whether prenatal metformin therapy can pre...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Tain, You-Lin, Wu, Kay L. H., Lee, Wei-Chia, Leu, Steve, Chan, Julie Y. H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979307/
https://ncbi.nlm.nih.gov/pubmed/29614026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041066
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